http://www.inquiriesjournal.com/keyword/gene-therapy Inquiries Journal provides undergraduate and graduate students around the world a platform for the wide dissemination of academic work over a range of core disciplines. en-us Fri, 15 May 2026 20:28:14 -0400 Fri, 15 May 2026 20:28:14 -0400 http://www.inquiriesjournal.com/articles/1432/the-importance-of-the-ras-raf-pathway-in-cancer-development By Gina M. Kelley - The Ras/Raf pathway is a crucial cell signaling pathway utilized by eukaryotic cells for growth and proliferation, and it is highly conserved amongst all eukaryotic organisms. Mutations in this pathway lead to uncontrolled growth and proliferation of cancerous cells, effectively giving them a major advantage over normally functioning cells. Not surprisingly, numerous specific mutations and epigenetic changes to these proto-oncogenes contribute to carcinogenesis in colon, skin, breast, lung, and other cancers. In this review, I explore the role of the Ras/Raf pathway in many different types of... Mon, 15 Aug 2016 05:51 EDT http://www.inquiriesjournal.com/articles/1432/the-importance-of-the-ras-raf-pathway-in-cancer-development http://www.inquiriesjournal.com/articles/914/gene-therapy-current-treatment-options-and-likely-near-term-developments By Mark T. Edwards - Gene therapy cells usually treats somatic cells and although originally devised to treat inherited disorders (Evans & Robbins, 1995), most gene therapy now benefits cancer patients. It is also used to treat acquired immune disorders, arthritis and hemophilia (Evans & Robbins, 1995; Mountain, 2000). Gene therapy is an attractive proposition since certain Ribonucleic acids (RNAs) or proteins provide effective treatments but are traditionally difficult to deliver effectively. Conventional treatments for some disorders are invasive, unpleasant, frequently ineffective and often have side effects... Mon, 15 Sep 2014 10:35 EDT http://www.inquiriesjournal.com/articles/914/gene-therapy-current-treatment-options-and-likely-near-term-developments http://www.inquiriesjournal.com/articles/199/using-stem-cell-and-gene-therapy-technologies-to-treat-parkinsons-disease By Heena Mulchandani - The sudden onset of Parkinsonism in drug addicts consuming the heroin- analogue MPTP in the 1980’s, led to its discovery as a potential cause of sporadic PD; indeed several chemical agents such as Rotenone have also received considerable attention (2). Although its etiology is still incompletely understood, the role of genetics in the pathogenesis of PD has been hotly debated for decades. The recent discovery of at least five genes (such as a-synuclein and parkin (Park-2))(3) together with animal lesion models (6-OHDA, MPTP, Rotenone) and human post mortem tissue analysis has polarized belief... Wed, 10 Mar 2010 08:45 EST http://www.inquiriesjournal.com/articles/199/using-stem-cell-and-gene-therapy-technologies-to-treat-parkinsons-disease