http://www.inquiriesjournal.com/keyword/dna Inquiries Journal provides undergraduate and graduate students around the world a platform for the wide dissemination of academic work over a range of core disciplines. en-us Mon, 18 May 2026 07:12:15 -0400 Mon, 18 May 2026 07:12:15 -0400 http://www.inquiriesjournal.com/articles/1850/genetic-coevolution-transposable-elements-and-their-impact-on-disease-development-in-humans By Gillian K. McNeil - Transposable elements (TEs), also referred to as ‘jumping genes’, are sequences of DNA located in the eukaryotic genome that have the ability to mobilize. This functional mobilization allows TEs to insert at random positions throughout the genome. It is currently being investigated whether or not the genetic instability caused by these relocations has effectively promoted the development of diseases in human populations, including rare genetic conditions and various types of cancer. This paper will review the theorized system of evolution of TEs in the eukaryotic genome, and the potential... Mon, 14 Dec 2020 10:55 EST http://www.inquiriesjournal.com/articles/1850/genetic-coevolution-transposable-elements-and-their-impact-on-disease-development-in-humans http://www.inquiriesjournal.com/articles/1748/studying-ancient-dna-to-understand-contemporary-disease By Wafaa Khatau - The study of DNA and genetics has always been a large mystery to many scientists. The current Ancient DNA (aDNA) research on human history is more complex than what can be inferred from modern DNA research. Scientists and researchers are constantly using modern day populations, and modern DNA to make inferences about past populations (Haber et al., 2016). With the new technologies available in ancient DNA, the study of past diseases and populations is more easily conducted with little to no contamination. Studying aDNA does not only tell us about current and past disease, but can also shed light... Thu, 20 Dec 2018 12:07 EST http://www.inquiriesjournal.com/articles/1748/studying-ancient-dna-to-understand-contemporary-disease http://www.inquiriesjournal.com/articles/1422/the-crispr-fantasy-flaws-in-current-metaphors-of-gene-modifying-technology By Alex J. Maben - CRISPR gene-modifying technology continues to revolutionize fields involving biological research. Rapid advancements, however, have sparked a vibrant bioethical debate scene. This research focuses on the effective usage of CRISPR metaphors in scientific communication. Specifically, I argue that the current figurative terminology—gene editing, targeting, scissors, etc.—exhibit underlying oversimplifications that bias public perspectives on CRISPR. Though the actual experimental science occurs in lab, the world learns about the discoveries through literary expression. It is thus... Mon, 13 Jun 2016 10:59 EDT http://www.inquiriesjournal.com/articles/1422/the-crispr-fantasy-flaws-in-current-metaphors-of-gene-modifying-technology http://www.inquiriesjournal.com/articles/1088/using-flow-cytometry-and-quantitative-real-time-pcr-to-investigate-the-role-of-il-1-in-t-cell-proliferation-and-hiv-1-reactivation By So Hee Moon - With the advent of antiretroviral therapy, suppressing the HIV-1 virus and stopping the progression of the disease are now possible. Even with long-term antiretroviral therapy, HIV reservoirs remain in individuals. These individuals experience an increase in inflammatory cytokines such as IL-6 and IL-1β that results in the proliferation of CD4 T-cells. In this study, we explored the relationship between inflammatory cytokine-induced proliferation and reactivation. To assess this relationship, we investigated the role of a specific inflammatory cytokine, IL-1β. It was concluded from our... Fri, 01 May 2015 12:00 EDT http://www.inquiriesjournal.com/articles/1088/using-flow-cytometry-and-quantitative-real-time-pcr-to-investigate-the-role-of-il-1-in-t-cell-proliferation-and-hiv-1-reactivation http://www.inquiriesjournal.com/articles/914/gene-therapy-current-treatment-options-and-likely-near-term-developments By Mark T. Edwards - Gene therapy cells usually treats somatic cells and although originally devised to treat inherited disorders (Evans & Robbins, 1995), most gene therapy now benefits cancer patients. It is also used to treat acquired immune disorders, arthritis and hemophilia (Evans & Robbins, 1995; Mountain, 2000). Gene therapy is an attractive proposition since certain Ribonucleic acids (RNAs) or proteins provide effective treatments but are traditionally difficult to deliver effectively. Conventional treatments for some disorders are invasive, unpleasant, frequently ineffective and often have side effects... Mon, 15 Sep 2014 10:35 EDT http://www.inquiriesjournal.com/articles/914/gene-therapy-current-treatment-options-and-likely-near-term-developments http://www.inquiriesjournal.com/articles/845/genome-profile-of-ambystoma-mexicanum By Patrick Wu - The Ambystoma mexicanum, commonly known as the axolotl, possesses extraordinary regenerative abilities and is capable of reconstituting limbs, retina, liver, and even minor regions of the brain (Muneoka et al., 2008). At the most elementary level, regeneration is mediated by a cascade of epigenetic processes. With the aid of recent advances in Next Generation Sequencing (NGS), a study was conducted to identify and sequence the gene expression responsible for axolotl regeneration. Tissue samples from denervated limbs and regeneration blastema of 36 axolotls were sequenced by Illumina. Following... Sat, 21 Dec 2013 02:28 EST http://www.inquiriesjournal.com/articles/845/genome-profile-of-ambystoma-mexicanum