http://www.inquiriesjournal.com/keyword/cancer Inquiries Journal provides undergraduate and graduate students around the world a platform for the wide dissemination of academic work over a range of core disciplines. en-us Sun, 17 May 2026 10:21:05 -0400 Sun, 17 May 2026 10:21:05 -0400 http://www.inquiriesjournal.com/articles/1916/cancer-epidemiology-in-romani-americans-a-review-of-the-current-literature By Naszrin Arani - Romanies are one of history’s most misunderstood ethnic populations. Since medieval times, they have faced slavery, forced assimilation, sterilization, genocide, and other forms of ethnic cleansing. Their cultural and historical persecution has led to adverse health outcomes. Studies on health inequality among Romanies have been conducted in the past, as well as fragmented research on their genetic predisposition to disease; however, there is a gap in available information regarding precancerous health risks, especially at the upstream, social end of the spectrum. Thus, their oppression... Thu, 14 Oct 2021 06:45 EDT http://www.inquiriesjournal.com/articles/1916/cancer-epidemiology-in-romani-americans-a-review-of-the-current-literature http://www.inquiriesjournal.com/articles/1850/genetic-coevolution-transposable-elements-and-their-impact-on-disease-development-in-humans By Gillian K. McNeil - Transposable elements (TEs), also referred to as ‘jumping genes’, are sequences of DNA located in the eukaryotic genome that have the ability to mobilize. This functional mobilization allows TEs to insert at random positions throughout the genome. It is currently being investigated whether or not the genetic instability caused by these relocations has effectively promoted the development of diseases in human populations, including rare genetic conditions and various types of cancer. This paper will review the theorized system of evolution of TEs in the eukaryotic genome, and the potential... Mon, 14 Dec 2020 10:55 EST http://www.inquiriesjournal.com/articles/1850/genetic-coevolution-transposable-elements-and-their-impact-on-disease-development-in-humans http://www.inquiriesjournal.com/articles/1631/causal-inference-to-ascertain-causes-of-metastasis-in-melanoma By Wesley Maddox - Skin cutaneous melanoma (SKCM) is a cancer affecting melanin-producing cells in the skin. It is a fairly common type of cancer with approximately 70,000 new cases diagnosed each year. Unlike many other cancer types, it has a fairly high survival rate with only approximately 8,000 deaths each year (The Cancer Genome Atlas, 2015). Similarly, many melanomas are diagnosed only after metastasis because many of those melanomas stay on the skin or other pigmented tissues and never metastasize. Much of the research regarding this disease has recently focused on attempting to understand and predict metastasis... Sat, 01 Apr 2017 12:00 EDT http://www.inquiriesjournal.com/articles/1631/causal-inference-to-ascertain-causes-of-metastasis-in-melanoma http://www.inquiriesjournal.com/articles/1432/the-importance-of-the-ras-raf-pathway-in-cancer-development By Gina M. Kelley - The Ras/Raf pathway is a crucial cell signaling pathway utilized by eukaryotic cells for growth and proliferation, and it is highly conserved amongst all eukaryotic organisms. Mutations in this pathway lead to uncontrolled growth and proliferation of cancerous cells, effectively giving them a major advantage over normally functioning cells. Not surprisingly, numerous specific mutations and epigenetic changes to these proto-oncogenes contribute to carcinogenesis in colon, skin, breast, lung, and other cancers. In this review, I explore the role of the Ras/Raf pathway in many different types of... Mon, 15 Aug 2016 05:51 EDT http://www.inquiriesjournal.com/articles/1432/the-importance-of-the-ras-raf-pathway-in-cancer-development http://www.inquiriesjournal.com/articles/914/gene-therapy-current-treatment-options-and-likely-near-term-developments By Mark T. Edwards - Gene therapy cells usually treats somatic cells and although originally devised to treat inherited disorders (Evans & Robbins, 1995), most gene therapy now benefits cancer patients. It is also used to treat acquired immune disorders, arthritis and hemophilia (Evans & Robbins, 1995; Mountain, 2000). Gene therapy is an attractive proposition since certain Ribonucleic acids (RNAs) or proteins provide effective treatments but are traditionally difficult to deliver effectively. Conventional treatments for some disorders are invasive, unpleasant, frequently ineffective and often have side effects... Mon, 15 Sep 2014 10:35 EDT http://www.inquiriesjournal.com/articles/914/gene-therapy-current-treatment-options-and-likely-near-term-developments http://www.inquiriesjournal.com/articles/810/a-genome-wide-search-for-proteins-that-control-the-balance-between-proliferation-and-differentiation-in-the-drosophila-ovary-an-in-vivo-model-system By Avanti Jakatdar - Understanding how progenitor cells stop proliferating and enter a differentiation pathway is a fundamental question in cancer and stem cell research today. The long term goal of this study is to identify proteins required for the transition between proliferation and differentiation in the Drosophila ovary, which is a model system for studying stem cells and tumor formation. To meet this objective, gene trap technology was used, which involves the insertion of green fluorescence protein (GFP) via a P element transposon called P{GFP}. When P{GFP} is inserted into an intron, it ̳traps' the protein... Fri, 22 Nov 2013 02:01 EST http://www.inquiriesjournal.com/articles/810/a-genome-wide-search-for-proteins-that-control-the-balance-between-proliferation-and-differentiation-in-the-drosophila-ovary-an-in-vivo-model-system http://www.inquiriesjournal.com/articles/592/a-q-methodological-study-of-male-attitudes-towards-testicular-cancer-and-testicular-self-examination By Ian D. Garner - This study used Q-methodology in order to explore the diverse range of meanings and understandings that young males construct in relation to testicular cancer (TC) and testicular self-examination (TSE). Using both conventional and online methods of Q-sorting, twenty-seven males aged 18 to 43 sorted a number of statements along a continuum from ‘strongly disagree’ to ‘strongly agree’. Statements represented a wide range of viewpoints concerning the risk factors, causes and symptoms of TC, popular ideas and common myths about TC and TSE, and the emotional consequences of... Tue, 08 Nov 2011 10:35 EST http://www.inquiriesjournal.com/articles/592/a-q-methodological-study-of-male-attitudes-towards-testicular-cancer-and-testicular-self-examination http://www.inquiriesjournal.com/articles/535/nuclear-weapons-testing-in-the-united-states-sacrificing-health-for-national-defense By Christopher Millson - As WWII ended, and the Cold War began, America began to strengthen its national defense against the Soviet Union. Alliances were created resulting in the formation of NATO and the Warsaw Pact. The United States began to create an arsenal of nuclear weapons in order to protect the freedom of its citizens, and the freedom of the world. But freedom from communism would come with a price for the American people, and they would become victims of the United States government’s most lethal form of national defense, nuclear weapons. Despite early public support, victims of the tests eventually reacted... Wed, 01 Jun 2011 09:20 EDT http://www.inquiriesjournal.com/articles/535/nuclear-weapons-testing-in-the-united-states-sacrificing-health-for-national-defense http://www.inquiriesjournal.com/articles/346/vitamin-d-insufficiency-due-to-insufficient-exposure-to-sunlight-and-related-pathology By Lana R. Johnson - Vitamin D has long been considered important for bone health because it aids in the absorption of calcium into the bone tissue. However, emerging research indicates that vitamin D is critical for other body systems to function properly, greatly increasing the scope of vitamin D’s importance. Because vitamin D is produced primarily by exposure to the sun, and because populations who live in northern latitudes have difficulty producing enough vitamin D due to reduced sun exposure, this essay will focus on the specific effects of vitamin D insufficiency experienced in northern regions such... Mon, 27 Dec 2010 10:29 EST http://www.inquiriesjournal.com/articles/346/vitamin-d-insufficiency-due-to-insufficient-exposure-to-sunlight-and-related-pathology